As per the reports Mpox is described in two two genetic clades, I and II. In it a clade is a broad grouping of viruses that has evolved over decades and is a genetic and clinically distinct group. Clade II was responsible for the 2022 outbreak, but clade Ib causes more severe disease.

Tedros said “But we are not dealing with one outbreak of one clade; we are dealing with several outbreaks of different clades in different countries with different modes of transmission and different levels of risk,”

WHO Contingency Fund for Emergencies, released $15 million, with $1.5 million for Use Listing process for both mpox vaccines and developed a regional response plan. The organization has signed off on the Emergency.

According to Tim Nguyen of the WHO Health Emergencies Program, Half a million doses of the vaccine are in stock, and another 2.4 million could possibly be produced by the end of the year. African Regional Emergency Director Dr. Abdou Salam Gueye added , the DRC and Nigeria will be the first to receive these vaccines.

The organization informed that vaccines are only part of the response; containing the spread will also require increased surveillance, diagnostics and research to fill “gaps in understanding.”

“We can stop transmission of mpox with a concerted effort using multiple approaches,” said Dr. Maria Van Kerkhove, director of WHO’s Department of Epidemic and Pandemic Preparedness and Prevention.

“There’s a lot of uncertainty. … We have an opportunity right now to really leverage this time and support our member states to support the research that needs to be done to understand this.”